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In receptor-binding and cellular-signaling research, MT-2 acts as a non-selective agonist across the melanocortin receptors: MC1R (associated with melanocyte pigmentation), MC3R and MC4R (central receptors implicated in energy-homeostasis and appetite research), and MC5R

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Goutzourelas N et al

Preclinical studies reveal VCs ability to reprogram the tumor microenvironment (TME) through collagen hydroxylation-mediated extracellular matrix remodeling, Treg suppression, and enhancement of CD8+ T cell infiltration

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