It is studied for its potential role in regulating cellular ageing processes, with particular interest in telomerase activity, telomere maintenance, and circadian rhythm regulation
This product is regularly used in our laboratory for reagent preparation tasks
World J Microbiol Biotechnol 33:169
Warth, J
Both genetic deletion and chemical inhibition of TRF1 have been shown to block the growth of lung carcinoma, glioblastoma, and renal cell carcinoma in mice without affecting mouse survival or tissue function, making TRF1 a potential therapeutic target in cancer 1,2,3
Many consistent alterations in the microbiome lead toward a causative or contributory role, and early interventions of microbiota could influence the progression of the disease and the severity of its symptoms