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Interestingly, higher concentrations such as 1 mM and 2 mM did not yield similar protective effects, indicating a dose-dependent response and identifying 0.1 mM as the optimal concentration for reactive oxygen species mitigation [2]

While initially developed to help regulate blood sugar levels, they have also been found to promote appetite suppression, leading to weight loss in patients

To illustrate, in reproductive health, GPx5 safeguards sperm from ROS during maturation, and deficiencies here have been linked to reduced fertility in animal models

Ghanemi A, Melouane A, Yoshioka M, St-Amand J

doi: 10.1111/dom.15972