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SPRED1 facilitates the localization of NF1 to the plasma membrane where it suppresses RAS signaling ( SPRED1 inactivating mutations and 12% undergo SPRED1 copy number loss ( SPRED1 alterations are insignificant in CM (79)

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[4] Career [edit] 2008 congressional run [edit] In 2008, Gordon was an unsuccessful candidate in the Republican primary for the United States House of Representatives for Wyoming's at-large congressional district seat held by Barbara Cubin, who was retiring

Table 10 Prognostic determinants in PDM

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