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This regulatory context is important: both medicines sit outside standard NHS prescribing pathways for most patients, and robust safety data in real-world UK populations is limited

Regulatory approval follows rigorous trials, and some GLP-1 drugs are approved for obesity management, others for type 2 diabetes

Additional studies highlight benefits for older adults and those with chronic kidney disease

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GLP-1 therapy is typically recommended for adults with a BMI of 30+, or 27+ with weight-related health issues like high blood pressure, high cholesterol, or type 2 diabetes

Prescriptions for these medications surged by over 300% from 2018 to 2023