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2015;11(1):e1004600

No specific antidote is available Supportive care remains the mainstay of management Strict adherence to recommended dosing guidelines is essential to minimize the risk of toxicity and unintended physiological disruption

Because of the theoretical benefits of maintaining antioxidant defenses to combat various acute and chronic diseases, reducing the consequences of aging and reducing tissue damage from exposure to environmental oxidants, therapeutic approaches to increase systemic and/or tissue-specific glutathione concentrations are of considerable investigational interest

Knowledge of the chemotherapy-related effects can be used to prevent disease occurrences and provide a reliable basis for clinical treatments

Additionally, you might find it beneficial to use niacinamide alongside vitamin C or AHAs

Production of vascular endothelial growth factor by murine macrophages: regulation by hypoxia, lactate, and the inducible nitric oxide synthase pathway