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N-Acetylcysteine (NAC): Potential Benefits, Known Risks, and More Note: The U.S

This review examines a broad spectrum of endogenous peptidereceptor systems that regulate metabolism, appetite, bonemusclefat crosstalk, neuroendocrine function, immune modulation, and tissue repair, yet lack approved therapeutic analogs

Shokeen says

Alpha-lipoic acid, an anti-obesity agent

doi: 10.1146/annurev.nutr.24.121803.063211 17 LouisPHoldGLFlintHJ

Of course, we want to be able to treat disease and relieve suffering to the best of our medical ability, but we should start asking questions about what actually determines optimal health, he said